RECURRENT SIGNATURE PATTERNS IN HIV-1 B CLADE ENVELOPE GLYCOPROTEINS ASSOCIATED WITH EITHER EARLY OR CHRONIC INFECTIONS.

Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections.

Here we have identified HIV-1 B clade Envelope (Env) amino acid signatures from early in infection that may be favored at transmission, as well as patterns of recurrent mutation in chronic infection that may reflect common pathways of immune evasion.To accomplish this, we compared thousands of sequences derived by single genome amplification from s

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Simarouba berteroana Krug & Urb. Extracts and Fractions Possess Anthelmintic Activity Against Eggs and Larvae of Multidrug-Resistant Haemonchus contortus

Gastrointestinal nematode infections significantly impact small ruminant production, causing Plush Toys substantial economic losses worldwide.The rising resistance to anthelmintics has led to the search for alternative treatments, including phytotherapeutic approaches.This study investigates the chemical composition and anthelmintic activity of cru

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Aberrant Spontaneous Brain Activity and its Association with Cognitive Function in Non-Obese Nonalcoholic Fatty Liver Disease: A Resting-State fMRI Study

Background: Nonalcoholic fatty liver disease (NAFLD) has been proven to be associated with an increased risk of cognitive impairment and dementia, and this association is more significant in non-obese NAFLD populations, but its pathogenesis remains unclear.Our study aimed to explore the abnormalities of spontaneous brain activity in non-obese NAFLD

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